IHEEZO

The IHEEZO Difference³

In a Phase III clinical trial for use in routine ophthalmic procedures, IHEEZO delivered.^*,2

Not all anesthesia
feels the same because

not all patients
are the same

Anesthesia in practice

When steps add up, outcomes can vary³

Current ocular anesthesia protocols vary in steps, application methods, and duration of effect. These differences don’t just impact procedural flow—they shape the patient’s experience, from the depth and consistency of anesthesia to the patient’s comfort during and after a procedure.

01
Prolonged prep time

Multiple drops administered up to 30 minutes before a procedure.⁴

02
More layers for more certainty

Pledgets or additional drop applications are often required to achieve sufficient anesthesia.⁴

03
Interference risks

High-viscosity gels can inhibit the antibacterial effect of povidone-iodine.³

04
Comfort that fades

Lingering irritation or dryness are common, potentially impacting the perceived recovery time.

Anesthesia in practice

When steps add up, outcomes can vary³

01
Prolonged prep time

Multiple drops administered up to 30 minutes before a procedure.⁴

02
More layers for more certainty

Pledgets or additional drop applications are often required to achieve sufficient anesthesia.⁴

03
Interference risks

High-viscosity gels can inhibit the antibacterial effect of povidone-iodine.⁴

04
Comfort that fades

Lingering irritation or dryness are common, potentially impacting the perceived recovery time.

When confidence, comfort, or efficiency are a priority, IHEEZO offers an easy choice.¹

Explore Access Options

Why IHEEZO

Comfort & confidence made simple^1,2

A modern take on ocular anesthesia, IHEEZO is designed for efficiency and comfort—delivering reliable, lasting anesthesia without adding complexity.^1,2

In a Phase III clinical trial evaluating IHEEZO for use in routine ophthalmic procedures, it was shown to deliver:^*,2

In this clinical trial, 100% of patients treated with IHEEZO maintained anesthesia without supplemental treatment.^**,1,2

See the Evidence

*The Phase III clinical trial was a randomized, prospective, multicenter, active-controlled, observer-masked study in 338 patients undergoing routine cataract surgery.

**In the clinical trial, no patient undergoing routine cataract surgery receiving IHEEZO required supplemental treatment to maintain anesthesia; this was not the case for patients receiving tetracaine. Supplemental treatment was defined as general anesthesia, intraoperative systemic analgesia, or local anesthesia. Though supplemental administration was not required by any patient in the clinical trial, IHEEZO may be reapplied as needed to maintain anesthesia.^1,2

Important Safety Information

IHEEZO is contraindicated in patients with a history of hypersensitivity to any component of this preparation.

IHEEZO should not be injected or intraocularly administered.

Patients should not touch the eye for at least 10 to 20 minutes after using anesthetic as accidental injuries can occur due to insensitivity of the eye.

Prolonged use of a topical ocular anesthetic may produce permanent corneal opacification and ulceration with accompanying visual loss.

Do not touch the dropper tip to any surface as this may contaminate the gel.

IHEEZO is indicated for administration under the direct supervision of a healthcare provider. IHEEZO is not intended for patient self-administration.

The most common adverse reactions in studies following IHEEZO administration (incidence greater than or equal to 5%) were mydriasis, conjunctival hyperemia, and eye irritation.

You are encouraged to report suspected adverse reactions to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For additional information about IHEEZO, please see the full Prescribing Information.